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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df5d7c5221734766783421bebb3c3c7a149b8c6489da8495df58a1458d9bdaf3' 
  AND token = '44qiJpAZsbNsuFLnoH15rNWXQ8tSKqqF5wN7q3/1Grc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}