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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dafc4f4e06498a62bc1f447624f1880175d88358596d296e9b18490c9d80b45' 
  AND token = 'mEp+1xWX7GluvcWBPLO1yrLoYINaF7SjBGmfeeJJCNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}