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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b61cddd388d53f928be1cd788d01498ea2c43e51664d1df080370e4e17a49666' 
  AND token = '4CTLnboN6VRjmyPV5NS+Hh7pUrGKL1wQnZE2Sk8hzGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}