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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '419c9cf344e7a8d094603324f01dad0a33185f3a5d929cc916602bc31f85d3e8' 
  AND token = 'LxTjIWm5P9BdQyVSVnGGTKF3Yu8WjgYEO2jIs9hWrfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}