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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b597b84cdd61e7c61367c3ad653bdd95787172be1db0ebd8a2c047fca66cbed4' 
  AND token = '2yL/nIFohhtQuLUrlw+IROXU+P7UGmS6LrJ14cq4C00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}