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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a21a7e7ba5796f93d3c733abbc37f6c30bb910926cefbe588ace8aad2cb91c49' 
  AND token = 'tRcD6D3MU61vT0jHOBvQCiHCpv166m5ejpki4EEk7nk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}