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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72f96814127ef24c71da52efcf65b8af9a3c3b95cbe2a7f98e3e970b652aaf4c' 
  AND token = 'cDBh2tOaUs5MrzdrcnCIVMSMz10t1+xzS7AXLXdJEhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}