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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bb7821106a28c9858bb2da5c8bc52ca17fd233e9ee9f54633894f4882978875' 
  AND token = 'YlwVyRJIjadtofHDjEUUzNnAPUM+5bJBXRFfjqp05Ak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}