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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8456aecc89ba9cd01a3b43d096e6a79c8538024662007e100f8781406dfd4948' 
  AND token = 'xpJnOWwVB6T06xVR3zTfjTekijuZwDzQePZD2/bX7pc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}