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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cb4b442d399822551f57519b70bc2df802bedcb9b74cec929b3a28f4f1e8ff2' 
  AND token = 'DfF8a9XorACOXiBJ1cIT5ktmT5i6hI6NlPTCesrdJQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}