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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dbb4e9a9163df8ba68e1098018e69de81240564996e89cdcf977a30159b1b929' 
  AND token = 'uE/UOhXD5YcJcD4of1PuHLWLv4SJKc8C2dHEDDhhbWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}