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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45a13a3c080ef2a7db13dca9ce58cd139a7f3187b126e326e5940e35ee4c00f3' 
  AND token = 'B/5WlleHgE/yO8zop9uV8ZagMOGLHNtisaOlmRAsqwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}