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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd27f3769f0b7b9c8b564f8e0b059004c473f7ef0a29468a271fd5139671fa3ae' 
  AND token = 'k4QyacGscYG+ZhwPHMJFo30hHnqnbXTJRMDJoMa3RxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}