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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '381507428e28d9a84fee30b985fbad9ca257990d4528d0f14b5b4be2cbc15ce8' 
  AND token = 'ZQPyqwRaEo7IrVBDS2KiMWVODqy7D73GUleJ1gtuchA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}