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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5601ae2f2d561e8b01024d1c7255db50b7e05e175fcb3804b70b38eea74135e2' 
  AND token = '5i+I1Qq9kesgYonVo8BzYF+P/biMz4Szyn0KwdT3voE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}