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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '397c48bb1b15f39fe268a1586bfe4b222e00350f19e4efbbbdd37808e8d4eb96' 
  AND token = 'h/Dvo8+9kmIUlDxn3bzMno8+pf4ve4lAdgDzl33l3k0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}