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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea5a05ddafd4e9beb9023e3ff5a291d48396bc5813dc7d7f9fd63b99d0d1a501' 
  AND token = 'nMP9Eb2yEWiUasdJnCR+yQi0D9wIYm4fwlVIfJWcpVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}