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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd25302eb5f03f24e9d467ad24ba39d7a34dde363b7b22ead839b3bb1c2c1037' 
  AND token = 'XXmqo06Y86yenOUQ6KfcPsHaMmdmtQwvRbZvhU7PKjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}