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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36153bfdf79580d242ceda9daa18b13b7af9ca2f9123021afdf2e8cebdae8143' 
  AND token = '4hUmK72hYXziDXmGLAilA35sh+E5CepJEWRbeVAXUNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}