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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49b745462bb8b27a37264b11bf7de3a47b2a32991f665fd6c1f5467c6f9fb7b3' 
  AND token = 'uaWqbt5l8XT5j4kLuxOQZQVnEUo122j5XTDk/o70HME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}