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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a67448d30b7951a50fb0011e436d47bf953d6c16b56bd65a8e6566f329ecfbf' 
  AND token = 'GnMGJcjcLrJrKzsYH4o0qbPak2feNF8PP07ngbB8zV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}