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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb03d7706cb6b8f7047f571c7fbb2f76b54db373a7f6aba189717b6a07ac708b' 
  AND token = 'o3ThtMYBNPv9USpyx7V+LtNv16Q6AfVrPkOgUxS7xSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}