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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a9345583792ac27165f4cc2294b28a0b62feb781b6f84c36410f7e9b164ad0c' 
  AND token = 'yKda/sMET28R6oAigPzDHtnsNqo9PqpwtzMgWF7Ed1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}