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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ff99af288c1e6d172be5b2d85d84a3a5fe60c9922e305e08a2de3e0b86ce44d' 
  AND token = 'rQrO5dmm3TA8vAh2I9tD4IK0v8Ma6gfvLAf9AuTmcTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}