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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07914134def380703b1d33a39cafd54427e3875ca4154cc8219b42e5b05b3c1f' 
  AND token = '9nBYtK5okAfZkd+w0oGsBFc0dqUBZ8Q4iUpOG1xxSX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}