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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2a33201ed1363e669f09ba6343d0c2821c0758c66f0d4840b7932c25176cf58' 
  AND token = '3HdyHCrfwxLnK9SCWRZEB8b3BWQqo39rTfB+ddjVanY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}