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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fad2b6b01c5742eee66e7d2ac8239173110fe6ca48f392923ae017b029e0153f' 
  AND token = 'D7GpkqM5RJ/n2rp2LaUUaV1AjX9CbPUx5pLQ0PvuGds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}