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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca5dbdd32f7a5610d74df83befcd303257f31531e814306a5145d51473e04c20' 
  AND token = 'ISPz8zUxqkn28wMho5so29/Gyd1nqxRV5AyuVHXsuos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}