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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d745f59f4af6fe392ecd2ae9f3d14143f66e693e4d2751d3c567098c07bef74' 
  AND token = 'Z64FrQNq4pSdfmpzMrcr0HqxcdA2XuOOTeVkTx5X7V4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}