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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '644f18b9fd0a306d5015e19e8907b036e8fbeedf39c20bfa422ab5d7792bd698' 
  AND token = 'AW2nAfSDBRHOqlyq1u6x17zmyG16LaODZYz7yB7WsQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}