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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c444d6a2e20918815f0fb66a46dc396ce398082db72db834c0002d8c813d248' 
  AND token = 'Hc6ZJ5dvjX8TezgX1I1yBM8sffjSvFxSKxweoYIL0Hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}