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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f38635c2bad486c4c6115532646463cdeb6f8dc23dd3082df034b9d374c11a7' 
  AND token = 'BxYKzOX9XLBC1C28phrnPUa6FnMUXXVTNbgqD4OUMpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}