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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3a1f53b1a1aaf7d51ceafe5df930197132afe9bd2636cb9ececca5a45c36dee' 
  AND token = 'J5WLSvFf+5uYKjbrdikfNSiirxf4hFUpAVW+h92bhPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}