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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '890b0184adff270acea01cf7a1f17bf15df5847f0d541bab52db5abf86ad07c6' 
  AND token = 'twBWcF2pCSm5PH0GjHYtY9hEIcT9bxkdVW8Nn1MxQ3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}