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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e3d871f71da6f573f705dbe21d824a1138c42ee096db3d307a6a4a1e3f0c583' 
  AND token = '4/AZvcBsx2YnX3CsdWiP2paapdhtTKxAB3VEtiWPCCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}