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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55b7f15b000ddd5c10fa34780e8ea7def6193b6b7333c239c33b7db8d3f847c6' 
  AND token = 'vEYpo/qeB+3RUaS5qXFMG4nrNpmLHWRom7TkBdZu+wE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}