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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9355b91258cfeb4f5c2bd3746ded39cee38da80125a51ccda9d2013cfd45e0f' 
  AND token = 'KYvokgZdO5D5dBXbYqmNQm/kHVe/gYe5lEw52exxgQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}