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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f0a9b88df447535961c9bf3eacdf814568c1ec0d730f42bf066b3f0fc87ff27' 
  AND token = 'ZEryurnByZMLq0mO2Ll4iAHFLiosEuX+W1jfE+k+Lzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}