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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '745f6b659ff1d1e064efbf6787717db1a6b9c9861968a9158f2edf41fc143a27' 
  AND token = 'ULYKlFhUPbh4870Gtlweo8hzo9WeYt/5L5mqb2nvz5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}