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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5781cefee11f00c268da2a83c2847500bb11f5a1de87e083b7c1e9c53e7ec4f6' 
  AND token = 'vbfo74WGe6qbKeknQJj9Rstpft0Rpdj6mw6Q3JgGTmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}