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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c27e39f26229367f0f5ae14f1cc6f52f6da6acf8babdc517703c3b280427ca9' 
  AND token = '+pVQIq+PJAlt91beqHFd+op9a0ouUxT57WqRm/nPar0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}