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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c42b2adf3515acbfcc527b8f9ebc1dee4fd5c6f15c417acf263c5e68f9a76482' 
  AND token = 'Op26FrWYrB2I56u0WJdoMNaDIOox2mCTaKQIFdwrnyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}