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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd765c38d4cd21426d2b8c050a2049817b38a5467b53521a245742757b639ad14' 
  AND token = 'cClT2QranpWbV7vQJsmvo4fdKuJEtLBlAaMenP4Ujd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}