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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73f77716f4cb7e9e69f73582b1b7feccb2534a25c76f3c780c68312ff7696735' 
  AND token = 'DBo6co2UwxX0SE/T+d7BQou3O/MKWQvIFzXvybYBn4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}