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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b59755b2d7ce174389b2a320aa78faf05c6a560413afc3ab02a5d93b4c38b2e' 
  AND token = 'UCVIDvphAx+bos2r+Lm1+nl2RPo8EWywBOgdTi5ABCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}