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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ce48acb71b674c4ef457dd1e5c5cc84cf63b1f40ece40412fd379454e20c701' 
  AND token = 'mmUsNZhL+RQwHeoLQs8ns6qV7U+HwVMeSiT5l65Aiew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}