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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a651b8f7b9e1456cca56a3cab59c1b18772fda9a16b94efcd257874370c32f5' 
  AND token = 'cFDSwLyaz5IZhCnlaCAYBKbE7HayDZQkQVsW64/kLa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}