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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc8742046d1ee7ea4456958592c8db6400c74b26536b63038eb26af7cd620849' 
  AND token = 'E10V3aS4GI94bcTxDXQS8+h3odTtxksZkctL0aDd2Mo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}