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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11f24510c21969f74e5313449fd057834bb3bc36b8caa36ce9281983269b740f' 
  AND token = 'v6B3rkf9KRGudtOEJnzoRuEcp8GNsFkHhfpUDtd6jRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}