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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0980b9810c0d33f50482046322c2853bbc116b194867e2124666b74ae1904c11' 
  AND token = '1YVzgDKVm1xwsWNyugQ4262dQZKcyYxn7xw/R0wMkGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}